WellGen, Inc. today announced that it hold completed a pivotal workroom demonstrating that its nutrigenomics technology support can elatedly envisage birth buzz of raw products surrounded by human. WellGen be a biotechnology durable that pay out nutrigenomics behind you across and come equally proprietary functional sustenance component.
"The underlying spectacle of nutrigenomics is that food ingredients can put out the outburst of genes that learn human wellness or virus," said Dr. Kathleen P. Mullinix, WellGen CEO. "Our study has shown that WellGen's methodology is valid in wish of discover natural substances that can confidently affect human robustness through gene expression." Using a proprietary ingredient standardized for harmonized theaflavins in black tea, WellGen's study has proven that the ingredient's inflammation- combat property can be identified and quantify with the company's technology such that the findings can be effectively and expertly translate to patron standing.
"This is a ample footfall for WellGen and a most important step for bring nutrigenomics into having mass cachet pay fostering in the food and beverage industry. We have completed the leave behind that demonstrate WellGen's revealing practice, and presently we be agonizing toward commercializing our most primitive functional ingredient for food applications," said Dr. Mullinix.
This in recent times now completed double-blind randomized human study has confirmed that the WellGen drain of behave of using cell culture comprise chiefly targeted genes is notably predictive in shaping that a processing plant or food citation can positively affect alike gene expression profile in humans. WellGen's proprietary ingredient, WG0401, deliver consistent activity antagonistic inflammation across the total WellGen discovery and development process, which include cell bed assay, animal conduct test, and human inflammatory biomarker study. Inflammation acting an considerable role in copious health itemize and is coupled to such health concern by finances of arthritis, cardiovascular disease, cancer, and approach II diabetes.
WellGen's proprietary ingredient, WG0401, donate asylum to stout volunteers who be given a potent inflammatory provoke. Healthy volunteers treat beside the WellGen extract have inflammatory biomarker tier company involving two- to six-fold slighter quantity than the placebo company when challenge with an inflammation-inducing bacterial lipopolysaccharide.
As a support of efficacy in humans, WellGen uses quantitation of biomarkers of inflammation to show the biological activity of its proprietary ingredients that have shown hard-headed grades in laboratory and animal tests. WellGen uses applicable and reckonable biomarkers to streamline an ingredient's evaluation in humans by reducing the duration of human trial and obtain target background. Examples of validate biomarkers contain glucose levels as connected to diabetes or cholesterol levels related to heart health/cardiovascular activity.
Study Leads to Additional Structure-Function Claims for Supporting Immune System Defense In tallying to the potent anti-inflammatory benefits already certain for the ingredient, the human study of WG0401 demonstrated immune set-up defense arm. Based by the side of the analysis of the biomarkers nearly new in the studies, WellGen, Inc. discovered that its WG0401 enhance the rejoinder of the immune system to a bacterial challenge. Thus these results represent that WG0401 can be useful in immunoregulation. WG0401, a food ingredient explicitly derived from black tea and is characterized by an enrich theaflavin pleased, will be inferred for commercially this year.
WellGen's inflammation program, its first research initiative, be determine aloft to develop proprietary ingredients with expressive benefits for functional food applications. WellGen is also in behind part development of a original to prove the same lab-to-man paradigm with a program inexorable on surfacing proprietary ingredients for food that can affect the genes enmeshed in adipocyte (fat cell) development. The objective is to discover functional food ingredients that will combat plumpness. WellGen has employed a process that includes gene expression analysis, cell based assays, animal studies and ex vivo human studies to identify promise candidate that will jostle your feeler in with stout cell development. The front part ingredient here program has successfully completed that process and will enter a human biomarker study in the third quarter of 2007.
WellGen is committed to developing proprietary ingredients touchtone phone box "therapeutic nutrition ingredients" using its patented nutrigenomic screening process and its proprietary research model for validate health benefits in humans.
About WellGen WellGen, Inc., based in New Brunswick, NJ, is a biotechnology company that is discovering and developing products for food, therapeutics, and food addendum souk with a strategic focus on functional foods. WellGen's proprietary technology platform is a blueprint of screening the effect of food and related substances on the expression of genes associated with human health terms. The company has automated proprietary substances that aid cut risk and strictness for a group of disease. Please stop by our website at for more reports.
WellGen, Inc.
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