Study Data Show Asacol(R) (Mesalamine) Is Effective In Treating All Extents Of Ulcerative Colitis Including Isolated Proctitis

Data from two Phase III clinical tribunal critical that Asacol, an oral, non-steroidal medication that belong to the common party of agents specified in position of 5-aminosalicylic acids (5-ASAs), be an celebrity and well-tolerated conduct in support of patients next to all extents of ulcerative colitis (UC), plus isolated proctitis. The grades show that patients with isolated proctitis who lug Asacol, dose at 2.4 g/day for six weeks, weathered significant restoration as unprompted as three weeks, and unceasing improvement at six weeks, of UC symptom. At six weeks 83 percent of patients have improvement rainy-day rectal bleeding, 75 percent had mucosal relaxing and 57 percent had reduced stool frequency. These background be presented at the Crohn's & Colitis Foundation of America's (CCFA) National Research and Clinical Conference/Sixth Annual Advances in the Inflammatory Bowel Diseases (IBD) Meeting.

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"A undisputed misperception among physician is that all oral 5-ASA be taught have incorporated proctitis patients; even so, this is not the crust," say Dr. Seymour Katz, Clinical Professor of Medicine at the New York University School of Medicine. "The sympathetic findings from these Asacol studies reassure physicians that Asacol is one treatment that have be proven effective for the period of the complete colon, even the most distal ration, and should give a hand shift in outlook physicians how to effectively treat their UC patients." Additional Study Details Data from two Phase III, multi-center, randomized, double-blind, 6-week, active-controlled studies of parallel ornamentation (ASCEND I&II) were integrated and analyzed. The aim of this analysis be to weigh against the efficacy of oral delayed-release Asacol dosed at 2.4 g/day to treat inaccessible UC flare in patients with isolated proctitis.

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